Category: Peptides Research
Research articles and educational content on peptides and longevity compounds, authored and reviewed by Dr. James, a board-certified neurosurgeon trained at Yale University, and Dr. Tom, a licensed pharmacist. All content is for research and educational purposes only.
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Confounding Variables in Growth Hormone Axis Peptide Studies
Written by: Dr. James Nguyen, MD (Neurosurgeon) Good peptide science depends on design as much as molecules. This post on Confounding Variables in Growth Hormone Axis Peptide Studies focuses on experimental structure, controls, and interpretation. Design Before Pipettes Confounding Variables in Growth Hormone Axis Peptide Studies starts with a clear question, predefined endpoint, and control…
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Statistical Power Issues in Small-n Peptide Research Studies
Written by: Dr. James Nguyen, MD (Neurosurgeon) Good peptide science depends on design as much as molecules. This post on Statistical Power Issues in Small-n Peptide Research Studies focuses on experimental structure, controls, and interpretation. Design Before Pipettes Statistical Power Issues in Small-n Peptide Research Studies starts with a clear question, predefined endpoint, and control…
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Dose-Response Curves in Lab Assays: EC50 and IC50 Basics
Written by: Dr. James Nguyen, MD (Neurosurgeon) Good peptide science depends on design as much as molecules. This post on Dose-Response Curves in Lab Assays focuses on experimental structure, controls, and interpretation. Design Before Pipettes Dose-Response Curves in Lab Assays starts with a clear question, predefined endpoint, and control plan. Peptides are easy to add…
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Positive and Negative Controls in Peptide Assay Design
Written by: Dr. James Nguyen, MD (Neurosurgeon) Good peptide science depends on design as much as molecules. This post on Positive and Negative Controls in Peptide Assay Design focuses on experimental structure, controls, and interpretation. Design Before Pipettes Positive and Negative Controls in Peptide Assay Design starts with a clear question, predefined endpoint, and control…
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Blinded Study Design Basics for Peptide Research Experiments
Written by: Dr. James Nguyen, MD (Neurosurgeon) Good peptide science depends on design as much as molecules. This post on Blinded Study Design Basics for Peptide Research Experiments focuses on experimental structure, controls, and interpretation. Design Before Pipettes Blinded Study Design Basics for Peptide Research Experiments starts with a clear question, predefined endpoint, and control…
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NMR Spectroscopy for Peptide Identity and Conformation Checks
Written by: Dr. Tom Do, PharmD NMR Spectroscopy for Peptide Identity and Conformation Checks is a practical lab topic that often decides whether peptide experiments reproduce. This explainer covers research-bench ideas only—not human-use guidance. Why This Matters at the Bench Small handling differences compound quickly with peptides: adsorption, oxidation, moisture uptake, and concentration errors can…
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Circular Dichroism: Checking Secondary Structure in Peptides
Written by: Dr. Tom Do, PharmD Circular Dichroism is a practical lab topic that often decides whether peptide experiments reproduce. This explainer covers research-bench ideas only—not human-use guidance. Why This Matters at the Bench Small handling differences compound quickly with peptides: adsorption, oxidation, moisture uptake, and concentration errors can look like biological effects. Standardizing circular…
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Amino Acid Analysis: Classic Composition Testing for Peptides
Written by: Dr. Tom Do, PharmD Quality control keeps peptide research honest. Amino Acid Analysis explains analytical thinking labs use to verify that vial contents match the label and remain fit for study. What In Specification Should Mean For amino acid analysis, criteria should be predefined: identity, purity, content, and appearance checks before a lot…
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Peptide Mapping Concepts: Confirming Sequence in Research QC
Written by: Dr. Tom Do, PharmD Quality control keeps peptide research honest. Peptide Mapping Concepts explains analytical thinking labs use to verify that vial contents match the label and remain fit for study. What In Specification Should Mean For peptide mapping concepts, criteria should be predefined: identity, purity, content, and appearance checks before a lot…
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ESI vs MALDI: Soft Ionization Choices for Peptide Identity
Written by: Dr. Tom Do, PharmD Quality control keeps peptide research honest. ESI vs MALDI explains analytical thinking labs use to verify that vial contents match the label and remain fit for study. What In Specification Should Mean For esi vs maldi, criteria should be predefined: identity, purity, content, and appearance checks before a lot…
